MEBEVERINE HYDROCHLORIDE
CAS 5630-53-5
Chemical Formula C₁₉H₂₆ClNO₃
Molecular Weight 343.87 g/mol
Mebeverine Hydrochloride (HCl) is an antispasmodic medication commonly used to treat gastrointestinal disorders such as irritable bowel syndrome (IBS) and other conditions that involve smooth muscle spasm.
It works by relaxing the muscles in the gut, relieving pain, discomfort, and cramping associated with these conditions. Mebeverine HCl is typically administered in oral form as tablets or capsules and is known for its ability to target the smooth muscle of the gastrointestinal tract without affecting the central nervous system.
Industrial Uses
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Treatment of Irritable Bowel Syndrome (IBS) :
- Relief of Abdominal Pain and Discomfort: Mebeverine HCl is commonly used to relieve symptoms of IBS, including abdominal pain, bloating, and discomfort. It works by relaxing the smooth muscle of the intestines, reducing spasms and improving bowel function.
- Reduction of Diarrhea and Constipation: It helps regulate bowel movements by reducing the spasms that can lead to diarrhea or constipation in IBS patients.
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Gastrointestinal Disorders :
- Spasms in the Digestive Tract: Mebeverine HCl is used to treat other gastrointestinal disorders that involve smooth muscle spasms, such as colitis or spastic colon. It can reduce pain and improve overall gastrointestinal motility.
- Post-operative Bowel Dysfunction: It is sometimes used after abdominal surgery to relieve bowel dysfunction caused by spasm and to aid in post-operative recovery.
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Symptom Management in Other Digestive Disorders :
- Functional Digestive Disorders: Mebeverine HCl is helpful in managing functional digestive disorders that cause discomfort, bloating, and irregular bowel movements, improving the quality of life for patients with these conditions.
Specifications
| CAS No | 5630-53-5 |
|---|---|
| EC Number | 227-085-3 |
| Molecular Formula | C₁₉H₂₆ClNO₃ |
| Molecular Weight | 343.87 g/mol |
| Appearance | White to off-white crystalline powder |
| Odor | Odorless |
| Solubility | Slightly soluble in water, soluble in ethanol |
| Melting Point | 134–136°C |
| Boiling Point | Not available |
| Density | Not applicable |
| pH (1% solution) | 4.5–6.5 |
| Assay (Purity) | ≥98% |
| Heavy Metals | ≤10 ppm |