IRBESARTAN
CAS 138402-11-6
Chemical Formula C₂₅H₂₈N₆O
Molecular Weight 428.53 g/mol
Irbesartan is an angiotensin II receptor antagonist (ARB) used primarily for the treatment of hypertension and diabetic nephropathy in patients with type 2 diabetes.
It works by blocking the effects of angiotensin II, thereby relaxing blood vessels and reducing blood pressure.
Industrial Uses
Pharmaceutical Industry
-
Tablets and Capsules :
- Formulated as monotherapy or in combination with other antihypertensive agents such as hydrochlorothiazide.
-
Hypertension Management: :
- Reduces the risk of cardiovascular events in patients with high blood pressure.
-
Diabetic Nephropathy: :
- Slows the progression of kidney disease in patients with type 2 diabetes and hypertension.
Specifications
| CAS No | 138402-11-6 |
|---|---|
| EC Number | 604-050-1 |
| Appearance | White to off-white crystalline powder |
| Molecular Weight | 428.53 g/mol |
| Molecular Formula | C₂₅H₂₈N₆O |
| Solubility | Practically insoluble in water; soluble in methanol and slightly soluble in ethanol |
| Purity | ≥99.0% (USP/BP/EP Standards) |
| Odor | Odorless |
| Melting Point | 180–181°C |
| Specific Optical Rotation | Not applicable |
| Loss on Drying | ≤0.5% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | ≤20 ppm |