AMOXICILLIN TRIHYDRATE (COMPACTED)
CAS 61336-70-7
Chemical Formula C₁₆H₁₉N₃O₅S·3H₂O
Molecular Weight 419.45 g/mol
Amoxicillin Trihydrate (Compacted) is a semi-synthetic, broad-spectrum antibiotic belonging to the penicillin class. The compacted form provides improved flowability and ease of handling during pharmaceutical manufacturing processes.
It retains the same active pharmaceutical properties as standard Amoxicillin Trihydrate and is commonly used in the production of tablets and capsules.
Industrial Uses
- Pharmaceutical Industry :
-
Tablets and Capsules :
- The compacted form is specifically designed for direct compression in tablet manufacturing.
- Improves production efficiency by enhancing flowability and reducing dust formation.
-
Suspensions :
- Utilized in oral liquid formulations for pediatric and geriatric patients.
- Effective against bacterial infections, including respiratory tract infections, urinary tract infections, and skin infections.
-
Veterinary Medicine :
- Used in formulations for treating bacterial infections in animals, particularly in oral dosage forms.
Specifications
| CAS No | 61336-70-7 |
|---|---|
| EC Number | 262-101-7 |
| Appearance | White to off-white compacted granules |
| Molecular Weight | 419.45 g/mol |
| Molecular Formula | C₁₆H₁₉N₃O₅S·3H₂O |
| Solubility | Slightly soluble in water, sparingly soluble in ethanol |
| Purity | ≥95.0% (USP/BP/EP Standards) |
| Odor | Odorless |
| Bulk Density | Typically 0.55–0.75 g/cm³ |
| pH (Solution) | 3.5–5.5 (in a 1% aqueous solution) |
| Loss on Drying | ≤3.0% |
| Residue on Ignition | ≤0.1% |
| Specific Optical Rotation | +290° to +315° |